Near Santander Airport

Santillana del Mar's historic center is closed to motor vehicles, its stone streets unchanged enough to have earned the town the nickname 'the town of three lies' — it is neither holy, flat, nor by the sea.

Potes sits at the confluence of four valleys in the Picos de Europa, its medieval bridges and a fortified tower marking the gateway into the mountain range.

Comillas pairs a medieval core with an unusual concentration of late-19th-century modernist architecture, including El Capricho, one of only a handful of buildings Antoni Gaudí completed outside Catalonia.

Liérganes sits on the Miera river beneath a row of grand 'indiano' mansions, built by villagers who returned wealthy from the Americas.